False-colored scanning electron micrograph of HIV particles (yellow) infecting a human H9 T cell (blue, turquoise)
US Food and Drug Administration (FDA) has approved the cobas HPV (Human Papillomavirus) Test which identifies women at highest risk for developing cervical cancer. This test will help physicians make early, more accurate decisions about patient care, which may prevent many women from developing this deadly disease. Continue reading “FDA Approves Roche’s HPV Test for Identifying Women at Highest Risk for Cervical Cancer”
MIT researchers have uncovered a critical difference between flu viruses that infect birds and humans, a discovery that could help scientists monitor the evolution of avian flu strains and aid in the development of vaccines against a deadly flu pandemic.
The researchers found that a virus’s ability to infect humans depends on whether it can bind to one specific shape of receptor on the surface of human respiratory cells.
Scientists have genetically engineered a mosquito to release a sea-cucumber protein into its gut which impairs the development of malaria parasites, according to research out today (21 December) in PLoS Pathogens. Researchers say this development is a step towards developing future methods of preventing the transmission of malaria.
University of Illinois at Chicago researchers have identified new sites on the bacterial cell’s protein-making machinery where antibiotics can be delivered to treat infections.
Continue reading “Researchers Find Promising New Targets for Antibiotics”
Biology textbooks are blunt—neutrophils are mindless killers. These white blood cells patrol the body and guard against infection by bacteria and fungi, identifying and destroying any invaders that cross their path. But new evidence, which may lead to better drugs to fight deadly pathogens, indicates that neutrophils might actually distinguish among their targets.
Scientists working in Switzerland, Vietnam and the United States say they have isolated antibodies that they hope could offer protection against several different strains of the virus simultaneously. Antibodies are used by our immune system to neutralise bacteria and viruses – in this case, the scientists have isolated antibodies that bird flu survivors in Vietnam produced to fight off the disease. Professor Antonio Lanzavecchia, at the Institute for Research in Biomedicine in Switzerland, says the antibodies have already proven effective in the lab and in mice and he is confident that they could be used in humans.
Read rest of the story at BBC News site.
In a study of non-human primates infected with the influenza virus that killed 50 million people in 1918, an international team of scientists has found a critical clue to how the virus killed so quickly and efficiently. Writing this week (Jan. 18, 2007) in the journal Nature, a team led by University of Wisconsin-Madison virologist Yoshihiro Kawaoka reveals how the 1918 virus – modern history’s most savage influenza strain – unleashes an immune response that destroys the lungs in a matter of days, leading to death.
The finding is important because it provides insight into how the virus that swept the world in the closing days of World War I was so efficiently deadly, claiming many of its victims people in the prime of life. The work suggests that it may be possible in future outbreaks of highly pathogenic flu to stem the tide of death through early intervention.
Continue reading “Study uncovers a lethal secret of 1918 influenza virus”
Scientists have finally deciphered the genome of the parasite causing trichomoniasis, a feat that is already providing new approaches to improve the diagnosis and treatment of this sexually transmitted disease. According to the World Health Organization trichomoniasis affects an estimated 170 million people a year and is an under-diagnosed global health problem.
Led by Jane Carlton, Ph.D., an Associate Professor in the Department of Medical Parasitology at New York University School of Medicine, the team of scientists took four years to crack the surprisingly large genome of the single-celled parasite Trichomonas vaginalis. They published the draft sequence of the parasite’s genome in the Jan. 12, 2007, issue of the journal Science.