Damaged and aged heart tissue of older heart failure patients was rejuvenated by stem cells modified by scientists, according to research presented at the American Heart Association’s Basic Cardiovascular Sciences 2012 Scientific Sessions.
“Since patients with heart failure are normally elderly, their cardiac stem cells aren’t very healthy,” said Sadia Mohsin, Ph.D., one of the study authors and a post-doctoral research scholar at San Diego State University’s Heart Institute in San Diego, Cal. “We modified these biopsied stem cells and made them healthier. It is like turning back the clock so these cells can thrive again.”
In this image, green represents myocytes newly formed by the transplanted cardiac stem cells. Red represents myocytes, blue shows the nuclei of the cells. Red and green colors together means that the transplanted cardiac stem cells have formed new myocytes. (Credit: Courtesy of the Journal of the American College of Cardiology)
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