False-colored scanning electron micrograph of HIV particles (yellow) infecting a human H9 T cell (blue, turquoise)
Success in the laboratory suggests that a new compound can point the way to preventing active tuberculosis in people infected with the latent form of the bacterium, says a team led by researchers at Weill Cornell Medical College in New York City. A drug with such properties could also be useful in treating people who already have tuberculosis by shortening the lengthy treatment period. The discovery also points to new ways of thinking about fighting bacterial infection, which is becoming increasingly resistant to traditional antibiotics.
MIT researchers have uncovered a critical difference between flu viruses that infect birds and humans, a discovery that could help scientists monitor the evolution of avian flu strains and aid in the development of vaccines against a deadly flu pandemic.
The researchers found that a virus’s ability to infect humans depends on whether it can bind to one specific shape of receptor on the surface of human respiratory cells.
Scientists have genetically engineered a mosquito to release a sea-cucumber protein into its gut which impairs the development of malaria parasites, according to research out today (21 December) in PLoS Pathogens. Researchers say this development is a step towards developing future methods of preventing the transmission of malaria.
University of Illinois at Chicago researchers have identified new sites on the bacterial cell’s protein-making machinery where antibiotics can be delivered to treat infections.
Continue reading “Researchers Find Promising New Targets for Antibiotics”
Biology textbooks are blunt—neutrophils are mindless killers. These white blood cells patrol the body and guard against infection by bacteria and fungi, identifying and destroying any invaders that cross their path. But new evidence, which may lead to better drugs to fight deadly pathogens, indicates that neutrophils might actually distinguish among their targets.
Scientists working in Switzerland, Vietnam and the United States say they have isolated antibodies that they hope could offer protection against several different strains of the virus simultaneously. Antibodies are used by our immune system to neutralise bacteria and viruses – in this case, the scientists have isolated antibodies that bird flu survivors in Vietnam produced to fight off the disease. Professor Antonio Lanzavecchia, at the Institute for Research in Biomedicine in Switzerland, says the antibodies have already proven effective in the lab and in mice and he is confident that they could be used in humans.
Read rest of the story at BBC News site.