Out-of-Africa migration selected novelty-seeking genes

AS HUMANS migrated out of Africa around 50,000 years ago and moved across the planet, evolution may have latched onto a gene linked to risk-taking and adventurousness.

The idea, first put forward by Chuansheng Chen at the University of California, Irvine, more than a decade ago, was originally met with scepticism. Now Luke Matthews of Harvard University and Paul Butler of Boston University have shown that a link between two versions of a specific gene and ancient migration patterns stands up to rigorous analysis.

The DRD4 gene codes for a dopamine receptor in the brain. It exists in several versions, or alleles, and studies have shown that people tend to have slightly different personality traits depending on which they have. The 4R allele, for instance, is associated with being even-tempered, reflective and prudent. The less common 7R and 2R versions have been linked to impulsive and exploratory behaviour, risk-taking and the ability to shrug off new situations. Matthews and Butler think that migrants with these versions were better able to deal with dangerous, fluctuating situations and more likely to survive and reproduce under those conditions.

via Out-of-Africa migration selected novelty-seeking genes – life – 06 May 2011 – New Scientist.

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