Reprogrammed Stem Cells Are Rife with Mutations

Adult cells that have been reprogrammed into stem cells harbor a number of genetic mutations, some of which appear in genes that have been linked to cancer. While scientists don’t yet know how this might affect the use of the cells in medicine, they say the findings show that the cells need to be studied much more extensively.

“As we think about using [these] cells for therapy, we will want to consider what kinds of screening tests we want to do,” says Lawrence Goldstein, a professor of molecular biology at the University of California, San Diego. One of the major concerns about stem-cell-based therapies has been whether they carry a risk of cancer; both stem cells and cancer cells are distinguished by their ability to continually divide.

via Reprogrammed Stem Cells Are Rife with Mutations – Technology Review.

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s