This is an outstanding 3D animation of HIV replication cycle. I especially loved the entry part, which is like watching a science fiction movie.
The animation is fairly accurate representation of what we know about the this viruses life cycle today, except the part on entry of viral DNA into nucleus. Based on our current knowledge, import of viral DNA into nucleus is not dependent on integrase but other viral and host proteins that are still elusive. Integrase is however necessary for the integration of virus DNA into host genome.
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Biosingularity 
NIce piece
nice video
Very informative and cool looking to boot!
I want to keep this video!!!
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Please I need to send me this video, because I work in prmotion and prevention of trasmitted infections diseases y HIV-AIDS,
Thanks
This was an amazing film, very very well done, and illustratively excellent…if you publish more of these I would like to be able to purvhase them for study purposes….nice job..
Allan M. Malkasian DDS
Oral and Maxillofacial Surgery
3826 Damsen Ave.
Visalia, Calif 93291
(559) 733-5792
Impressive film.
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I loved it! Can I see some animations on the brain?
ı wan to thıs vıdeo!thıs vıdeo my homework.you can send me ıam happy.
reverse transcriptase doesnt just run through the genome twice. its primed by cellular t-RNA (which anneals to the pbs sequence), then the five prime end is replicated, then rnase removes the hybridized, newly constructed primer and it(the primer) migrates to the 3′ end and the minus strand dna is produced (as rna is removed). Plus strand Dna primes the polypurine tract downstream of the env gene, and the five prime end of the plus strand is synthd by td dna dependent dna poly. Rnase degrades the trna and ppt before a second jump occurs, this time the plus strand of dna binds the pbs by the 3’end of the – dna strand– and only then do you get to synth the rest and have a dsdna viral genome
This is an amazing animation of HIV replication cycle. It is very informative and useful for training purposes. Can you please send it to me for teaching purposes?
Thx
Really amazing , How can I save these for offline viewing.
This is a fantastic animation of HIV replication cycle. Can you please send it to me for teaching purposes too.
Many thanks.
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I need this for a biology proyect!! can you send me the video? It`s amazing..
This is really cool stuff. Listening to it saved me a lot of work.
It is very useful educational film
Not only does this demonstration animate HIV viral replication, it demonstrates the central dogma of molecular biology which is Replication of DNA, Transcription of RNA, and Translation into protein synthesis. Excellent work.
beautiful animation for teaching!
Good animation for learning and teaching or explaining. how do i get it for offline use?
A fantastic Education Material on understanding the concept of Viral Replication.
I will be greatful If I could get a Downloadable Animation for the benefit of our Students.
I really appreciate ur work and the best animation i have ever seen in my life .thanks
me parece excelente el video, muy ilustrativo, deja muy claro como sucede la replicación viral y como se inhibe por medio del TARV. Me gustaría tenerlo para poder mostrarselo a mis pacientes. I don’t speak english very good. How I can download the video for the benefit of mine patients?
how can i have this video im working on retrovirus..send to my email plz. Thank you
This is a great movie – is it available for teaching purposes?
How can I get this animation offline. Is it possible to have on the desktop as screensaver?
Same, here loved it, but was thinking how i can have this to share it during my prensentation to Medical and nusring students?
very interesting can send to my email as soon as possible coz i need it 4 homework purposes
i am doing pg. how can i have this video offline please send me this video.
I would love a copy of this video, add to my website as well as to us in presentation when I speak. This is probably one of the best representations I have seen to date!
it is a very good explanation with 3d animation
This is an amazing video. It would be of great benefit to new students studying and working in the field of HIV. Could I be sent a copy via email. I would happily pay for a copy.
The best and highly informative animation
The BEST YouTube animation (not just animation, the best video ever) I have ever seen. Thank you very much. I intend to upload the same should I wish to discuss about HIV in my blog.
This video is great! If you are making downloadable copies available for teaching I would love to have one.
Thank you!
Nice and well done video. Very usefull in my biochemistry class. Thanks for sharing.
This is an amazing animation. It will help me a lot in my study and also presentation if you could send me a copy of it by email.
Thank you
a wonderful animation! was really useful for my seminar
I like to have this video because it will be useful in teaching.
thanks alot.
its excellent & marvellous animated video which gives a very clear information visually….. please let it get downloaded such that it can reach all over the world
if downloaded can be utilised by HIV field workers as general information to public
thank you
AMAZING video! Very cool and well done, thanks!
Simply Excellent!
This is excellent. I would like to use it in a lecture. I am not sure of how to do that.
its very informative and well done,
but too much technical jargon
not suitable fr every 1 as not every 1 will understand wats goin on
I guess it is alright. The only problem is that reverse transcriptase enzyme actually attatches to the anticodon of the virus. Know what I am saying?
simply brilliant!!!!!!!!
This is excellent. I would like to use it in a lecture. I am not sure of how to do that.
Simply Brilliant! I am a brain surgeon and I simply love it. Beautiful piece of work. It is absolutely positively amazing.
It’s a beautifully designed movie, and the graphics are amazing.
However, there are several factual errors. Some of these (import of HIV genome into nucleus, mechanism by which reverse-transcription occurs) have been pointed out.
In addition, the capsid doesn’t form around the viral RNA before budding. The entire (purple) protein, known as ‘Gag’ before it is chopped up by the protease, forms a shell around the viral RNA as the virus buds from the host cell. The host cell membrane, which by now has viral entry proteins embedded in it, coats this shell, and the immature virus buds.
Some time after the virus buds out of the host cell, the protease, which is packaged inside the virus, starts chopping up the Gag protein into fragments, some of which finally form a capsid around the viral RNA. The virus in this state, with a fully-formed capsid, is now mature, and is capable of infecting other cells.
nice blog
thanks
I want have, this video in my email address, some one help me spend me in my e mail address
thank you
where’s the link to the video???
The video is embedded at the top of the page.
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Every time I come to biosingularity.wordpress.com you have another exciting post up. A friend of mine was talking to me about this topic a couple weeks ago, so I think I will e-mail my friend the url here and see what they say.
excellent video that was well done, how can i access it offline
hi sir i like to have pls send to my mail. its so nice really
Next time I would suggest more effective segmentation of the article. An outstanding piece usually requires focus, and my own is not what it was in the past.